A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated

Authors: Ashcroft A, Ellard S, Hattersley AT, Mannikko R, Sansom M, Stansfeld P
Published: 1st July 2011
Theme: Complex Care
Type: Paper
DOI: 10.1113/jphysiol.2011.209700 Â Â

Reference:

Mannikko R, Stansfeld PJ, Ashcroft AS, Hattersley AT, Sansom MS, Ellard S, Ashcroft FM. A conserved tryptophan at the membrane-water interface acts as a gatekeeper for Kir6.2/SUR1 channels and causes neonatal diabetes when mutated. Journal of Physiology 2011;589(13): 3071-3083.