Will delays in treatment jeopardize the population benefit from extending the time window for stroke thrombolysis?

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Pitt M, Monks T, Agarwal P, Worthington D, Ford GA, Lees KR, Stein K, James MA. Will delays in treatment jeopardize the population benefit from extending the time window for stroke thrombolysis? Stroke 2012;43(11): 2992-2997.