Expertise
Statistics
Biography
I joined PenCLAHRC in April 2010 as a senior statistician and have provided input into the design, development and execution of a range of projects. In 2012 I was appointed to a Chair in Medical Statistics at the University of Exeter Medical School where I currently lead the Health Statistics group. A particular focus of my research is developing and applying methods for making more effective use of routinely collected health data. I lead the MRC-funded Extending the Prior Event Rate Ratio (EPERR) project investigating quasi-experimental methods for addressing sources of bias when evaluating medical interventions using Primary Care databases. The outputs of this research could help to enhance decision making relating to planning of future randomised controlled trials, as well as guiding treatment options in the clinic.
Projects
Publications
- The agreement between the referrer, practitioner and research diagnosis of autistic spectrum conditions among children attending child and adolescent mental health services
- Evaluation of a complex intervention (Engager) for prisoners with common mental health problems, near to and after release: study protocol for a randomised controlled trial
- The relationship between exclusion from school and mental health: a secondary analysis of the British Child and Adolescent Mental Health Surveys 2004 and 2007
- Mechanisms of action in mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR) in people with physical and/or psychological conditions: A systematic review
- Variation in referral and access to new psychological therapy services by age: an empirical quantitative study
- Prior event rate ratio adjustment for hidden confounding in observational studies of treatment effectiveness: a pairwise Cox likelihood approach
- Supporting Kids, avoiding Problems’ (SKIP), Relationships between school exclusion, psychopathology, development and attainment, a case control study
- Vitamin D and Dementia
- Vitamin D and the risk of dementia and Alzheimer disease
- A repeated cross-sectional study examining the school impact on child weight status.
- “The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value”
- The Work and Social Adjustment Scale: Reliability, Sensitivity, and Value
- Effectiveness of enzyme replacement therapy in adults with late-onset Pompe disease: results from the NCS-LSD cohort study.
- Long-term effectiveness of enzyme replacement therapy in Fabry disease: results from the NCS-LSD cohort study.
- Long-term effectiveness of enzyme replacement therapy in children with Gaucher disease: results from the NCS-LSD cohort study
- Long-term effectiveness of enzyme replacement therapy in adults with Gaucher disease: results from the NCS-LSD cohort study
- The NCS-LSD cohort study: a description of the methods and analyses used to assess the long-term effectiveness of enzyme replacement therapy and substrate reduction therapy in patients with Lysosomal Storage Disorders
- Systematic review and meta-analysis of the association between childhood overweight and obesity and primary school diet and physical activity policies
- Longer Lived Parents: Protective Associations With Cancer Incidence and Overall Mortality
- Toward a gene expression biomarker set for human biological age
- The effectiveness and cost-effectiveness of enzyme and substrate replacement therapies: a longitudinal cohort study of people with lysosomal storage disorders
- Effectiveness of intervention on physical activity of children: systematic review and meta-analysis of controlled trials with objectively measured outcomes (EarlyBird 54)
- Polymorphisms in LMNA and near a SERPINA gene cluster are associated with cognitive function in older people
- Can standardized diagnostic assessment be a useful adjunct to clinical assessment in child mental health services? A randomized controlled trial of disclosure of the Development and Well-Being Assessment to practitioners
- The reliability and validity of the Everyday Feelings Questionnaire in a clinical population
- Urinary bisphenol a concentration and angiography-defined coronary artery stenosis
- PMO-161?Hepatitis E (HEV) in South West England. Geographical, environmental and social factors: a case control study
- (COCOA) Care for Offenders Continuity of Access
- Leukocyte CCR2 expression is associated with mini-mental state examination (MMSE) score in older adults
- Urinary bisphenol A concentration and risk of future coronary artery disease in apparently healthy men and women
- CCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strength
- Congenital keratoconjunctivitis sicca and ichthyosiform dermatosis in 25 Cavalier King Charles spaniel dogs. Part I: clinical signs, histopathology, and inheritance
- Bisphenol A exposure is associated with in vivo estrogenic gene expression in adults
- Improved curve fits to summary survival data: application to economic evaluation of health technologies
- An exercise intervention to prevent falls in people with Parkinson’s disease: a pragmatic randomised controlled trial
- The coronary artery disease-associated 9p21 variant and later life 20-year survival to cohort extinction
- Hepatitis E virus coinfection in patients with HIV infection
- Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
- Self-care in people with long term health problems: a community based survey
- Predictors of extraordinary survival in the Iowa established populations for epidemiologic study of the elderly: cohort follow-up to ‘Extinction’
- Changes in resting energy expenditure and their relationship to insulin resistance and weight gain: a longitudinal study in pre-pubertal children (EarlyBird 17)
- Fatness leads to inactivity, but inactivity does not lead to fatness: a longitudinal study in children (EarlyBird 45)
- Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the U.S. National Health and Nutrition Examination Survey
- Association of urinary bisphenol a concentration with heart disease: evidence from NHANES 2003/06
- National mortality rates from chronic liver disease and consumption of alcohol and pig meat
- Association of Urinary Bisphenol A Concentration With Medical Disorders and Laboratory Abnormalities in Adults